About Us

Diagnostic Evidence Co-operative (DEC) London is one of four NIHR centres in England that generate evidence to support the development of diagnostic tests. We achieve this by developing research methods that help to expedite the process of evidence generation – and by collaborating with various stakeholders to support this process. We work with clinicians to identify unmet needs for diagnostics – and we work with diagnostic test developers to explore the utility of specific tests within UK NHS settings. By facilitating the adoption of new, improved tests into clinical practice we hope to improve the quality of patient care within the NHS.

Leadership & Administration

Prof. George Hanna

Director and lead of Gut Health and Cancer themes

Elias Zapantis

Business and Marketing Manager

Methodology Team

Prof. Peter Buckle

Human Factors expert and Principal Research Fellow at Imperial College

Dr. Simone Borsci

Human Factors expert and Research Fellow at Imperial College

Dr. Simon Walne

Human Factors expert and Research Fellow at Imperial College

Dr. Melody Ni

Expert in Decision theory and Senior Research Associate at Imperial College

Ijeoma Uchegbu

Health Economist at Imperial College

Wayne Smith

Health Economist at Imperial College

Dr Mamta K. Bajre

Health Economist at Imperial College

Prof. James Barlow

Expert in technology adoption and Professor of Technology and Innovation Management at Imperial College Business School

Frances Domingo

Research Nurse at Imperial College

Clinical Team

Prof. Azeem Majeed

Primary Care Theme Lead and Professor of Primary Care and Public Health at Imperial College

Dr. Austen El-Osta

Primary care Research Manager at Imperial College

Prof. Alison Holmes

Respiratory and Infectious Diseases Theme Lead and Director of Infection Control at Imperial College NHS Trust

Dr. Graham Cooke

Scientist in the Division of Infectious Diseases at Imperial College NHS Trust

Prof. Onn Min Kon

Reader in Respiratory Medicine and Adjunct Professor at Imperial College

Prof. Des Johnston

Metabolic Medicine Theme Lead and Vice Dean (Education) for the Faculty of Medicine at Imperial College

Dr. Nick Oliver

Clinical Senior Lecturer in Metabolic Medicine at Imperial College

Dr. Shivani Misra

Clinical Research Fellow in Metabolic Medicine and Pathology at Imperial College

Prof. Anthony Gordon

Emergency Medicine and Trauma Theme Lead and Reader in Critical Care Medicine at Imperial College

Dr. Ian Maconochie

Consultant in Paediatric Accident & Emergency Medicine at Imperial College NHS Trust

Mansoor Khan

Consultant Trauma Surgeon at Imperial College

Prof. Tiong Ghee Teoh

Maternal Health Theme Lead and consultant Obstetrician and Gynaecologist at Imperial College NHS Trust

Dr. Robert Boyle

Paediatrics Theme Lead and Director of the Clinical Research Facility for Children and Young People at Imperial College NHS Trust

Patient and Public Management

Prof. Roger Kneebone

Patient and Public Involvement Theme Lead and Professor of Surgical Education and Engagement Science

Ijeoma Uchegbu

Patient and Public Manager and Health Economist at Imperial College

Momoko Sato

Patient and Public Assistant Manager and Research Assistant at Imperial College

Patient and Public Lay Board

Dr Alison Allam

PPIEP Lay Board member

Miss Deb Smith

PPIEP Lay Board member

Mrs Diane Eaton

PPIEP Lay Board member

Mrs Marney Williams

PPIEP Lay Board member

Mr Maurice Hoffman

PPIEP Lay Board member

Our Approach

In order to work effectively, diagnostic tests must interact with a wide range of different aspects of the healthcare system, including people, technologies, and processes.

By systematically analysing diagnostics’ interactions with the healthcare system, our Lean Systems Approach for Innovation (LSAI) generates data on a wide range of factors likely to be important for the adoption of the test into clinical practice. These include the clinical utility of the test (e.g. sensitivity, specificity), user needs and preferences, aspects of test design, technology compatibility, and economic factors.

Our multidisciplinary expertise – which includes clinical, technology, human factors, and health economics – provides a unique basis for examining the range of factors that might affect the adoption and integration of new diagnostics.

The diagram below illustrates the development pathway for diagnostics, as well as some the main types of expertise required to support this development. All such expertise can be found at DEC London.


Our Partners

We work with industry bodies, clinical partners, national agancies and other NIHR infrastructures – including the other Diagnostic Evidence Co-operatives (DECs), Health Technology Centres (HTCs) – and accademic institutions and networks to promote new diagnostics evaluation methods.